SciMed
Rotary Microtome for Biological Laboratory — Paraffin Sectioning, Precision 1-25 μm Thickness
Rotary Microtome for Biological Laboratory — Paraffin Sectioning, Precision 1-25 μm Thickness
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Precision rotary microtome for histopathology tissue sectioning — cuts paraffin-embedded tissue blocks (and plastic-embedded specimens with modification) into 1-25 μm slices for microscopic examination. Manual advance mechanism with adjustable section thickness in 1 μm increments (typical operating range 1-25 μm, coarse feed to 50 μm), heavy cast-iron base for vibration damping during precision cuts, standard universal specimen clamp accepts routine paraffin blocks. Made in India. $1,199 direct — versus $6,500-$18,000 for Leica RM2125 RTS / Thermo Scientific HM325 / Sakura Accu-Cut manual microtomes.
Specifications
| Type | Rotary microtome, manual advance |
|---|---|
| Section thickness range | 1 - 25 μm (in 1 μm increments); coarse feed to 50 μm |
| Section thickness precision | ±0.5 μm typical |
| Specimen types | Paraffin-embedded tissue (routine), plastic-embedded (with modified blade), frozen tissue (adjacent cryostat recommended) |
| Specimen clamp | Universal — accepts standard paraffin blocks up to 40 × 30 × 15 mm |
| Blade type | Standard steel microtome blade (disposable + reusable options) |
| Blade holder | Adjustable angle (typically 4-8° set-back angle for paraffin) |
| Advance mechanism | Manual advance wheel (hand-operated) |
| Base | Heavy cast-iron construction — vibration damping for precision cuts |
| Vertical stroke | ~55 mm (typical for rotary microtomes) |
| Dimensions | ~450 × 350 × 300 mm |
| Weight | ~28 kg (heavy for stability) |
| Power | Manual — no electrical power required |
| Warranty | 1-year parts + labor · Advance mechanism 3-year |
Clinical applications
- Histopathology — routine tissue sectioning for H&E staining (Hematoxylin & Eosin)
- Surgical pathology — biopsy + surgical specimen tissue processing
- Cytopathology — cell block sectioning
- Immunohistochemistry (IHC) — thin sections for antibody staining
- Special stains — PAS, GMS, Trichrome, Congo Red preparation
- Frozen sections — with adjacent cryostat, rapid intraoperative diagnosis
- Autopsy pathology — post-mortem tissue examination
- Veterinary pathology — animal tissue diagnostic + research
- Research histology — animal model tissue examination
- Dental + oral pathology — soft tissue biopsy sectioning
- Dermatopathology — skin biopsy sectioning
- Toxicological histopathology — pharma safety studies
Best for
- Community hospital pathology labs
- Small + medium diagnostic pathology labs
- Veterinary diagnostic + reference labs
- University histology + pathology teaching programs
- Medical + veterinary school teaching lanes
- Research histology + animal facility support labs
- Forensic pathology labs (autopsy tissue)
- Pharmaceutical safety / toxicology studies
- International pathology labs (India, LATAM, MENA, SE Asia, Sub-Saharan Africa) via DDP
- NGO / global health pathology training (WHO, PAHO, MSF, Partners in Health)
Buying for a pathology lab, hospital, or academic program?
- Volume pricing on 3+ orders — teaching lab fleets, multi-hospital pathology builds
- Net-30 invoicing for verified hospitals, universities, diagnostic labs
- SAM.gov / VA / DoD compliant procurement — VA + military pathology
- Compatible with standard Leica / Thermo blade holders + replacement blades
- Replacement disposable blades (200/box ~$85), specimen clamps, advance mechanism parts stocked
- International DDP shipping — huge pathology + diagnostic build-out markets globally
- NGO / global health pricing for verified pathology training programs
- Extended 3-year service contracts for high-volume clinical labs
FAQ
How does this compare to a Leica RM2125?
Feature parity on the essential histopathology function — precision paraffin sectioning at 1-25 μm, heavy cast-iron base, universal specimen clamp, manual advance mechanism. Leica RM2125 has more polished operator interface, integrated waste blade holder, and premium build quality. Price differential: $1,199 vs $8,000-$12,000. For community hospitals, veterinary labs, and international pathology training, SciMed delivers 90% of clinical value at 12-15% of Leica pricing.
Is this an automated / motorized microtome?
No — this is a manual advance microtome. Operator turns the hand wheel to advance the block and cut sections. For high-volume production labs (100+ blocks/day), semi-automated (motorized advance) or fully automated microtomes are preferred. For teaching, veterinary, community, and research settings, manual advance is fully adequate.
What blade type does this take?
Standard microtome blade holders — accepts both traditional reusable knives (with knife holder) and disposable blade cassettes (Leica-compatible + Thermo-compatible). Blades sold separately, ~$85 per box of 200.
Can I cut frozen sections?
Not directly — frozen section requires a cryostat (temperature-controlled microtome chamber at -20 to -30°C). This unit is a room-temperature rotary microtome for paraffin + plastic. For frozen sections, look for cryostats separately.
What section thickness range?
1 μm minimum (very thin — for IHC + EM prep), 25 μm typical maximum (for standard H&E). Coarse feed to 50 μm for trimming block face. Routine H&E sectioning is typically 4-5 μm.
How is this shipped?
US: LTL freight (~28 kg boxed). International: DHL Express DDP or ocean freight DDP. Ships to India, LATAM, MENA, SE Asia, GCC, Sub-Saharan Africa — major pathology capacity expansion markets.
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